Figure 3

Representative GMSP with a single-peak (monoclonal expansion) of TCRBV families in CD4⁺CD25⁺Treg from ACLF and CHB patients. The TCRBV gene families in the top graphs corresponding to P43 (BV20), P70 (BV20), P51 (BV18), P46 (BV13.1), P25 (BV12), and P47 (BV11). The TCRBVs shown in the bottom graphs correspond to P20 (BV22), P17 (BV20), P57 (BV18), P45 (BV17), P17 (BV15), and P44 (BV13.1). The correspond amino acid sequences are shown in Table 3. The melting temperature is on the x-axis of each plot. The negative first derivative of the decrease in fluorescence as a function of temperature (−dF/dT) is shown on the y-axis.