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Correction to: miR-200c Inhibits invasion, migration and proliferation of bladder cancer cells through down-regulation of BMI-1 and E2F3

Journal of Translational Medicine volume 20, Article number: 153 (2022) Cite this article

The Original Article was published on 04 November 2014

Correction to: Journal of Translational Medicine (2014) 12:305 https://doi.org/10.1186/s12967-014-0305-z

Following publication of the original article [1], we have been notified by the authors that Figures in the article should be revised. Correct figures are mentioned in this article (Figs. 1, 2 and 3).

Fig. 1
figure 1

miR-200c was down-regulated in bladder cancer tissues and cell lines. A Relative expression of miR-200c in 15 pairs of Bladder Cancer tissues and their corresponding adjacent noncancerous tissues (ANT). B Different expressions of miR-200c in immortalized human nephric tubule cell line SV-HUC-1 and four bladder cancer cell lines (5637, TCC-SUP, T24, UMUC-3)

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Fig. 2
figure 2

Up-regulated miR-200c inhibited proliferation, migration and invasion in bladder cancer cells. A Entivirus carrying miR-200c plasmid and the control plasmid were persistently co-transfected into UMUC-3 and T24 cells. Measurements by real-time RT-PCR of miR-200c confirmed our success of transduction and were obviously higher than the control group in both cell lines. B CCK-8 assays revealed cell growth differences of indicated cell lines. C Colony formation assay in T24 and UMUC-3 cells. D Measurement of in vitro cell migration by “wound-healing” assay. Representative pictures (left) and quantification (right) for same single spot in indicated cell lines. E Transwell migration assays in indicated engineered cell lines. F Transwell invasion assays in indicated engineered cell lines. Data are presented as mean ± SD from 3 independent experiments. *P < 0.05; **P < 0.01. ***P < 0.001; DAPI, 4′,6-diamidino-2-phenylindole

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Fig. 3
figure 3

Down-regulated miR-200c promoted growth and metastasis in bladder cancer cells. A Antagonizing endogenous miR-200c in UMUC-3 and T24 cells. Level of miR-200c was measured by real-time PCR and miR-200c was obviously antagonized in the both cell lines. B CCK-8 assays revealed cell proliferation differences of T24 and UMUC-3 cells. C Colony formation assay in indicated cell lines. D Measurement of in vitro cell migration by wound-healing assay. E Transwell migration assays in T24 and UMUC-3 cells. F Transwell invasion cells in T24 and UMUC-3 cells. Data are presented as mean ± SD from 3 independent experiments. *P < 0.05; **P < 0.01. ***P < 0.001; DAPI, 4′,6-diamidino-2-phenylindole

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Reference

  1. Liu L, Qiu M, Tan G, Liang Z, Qin Y, Chen L, Chen H, Liu J. miR-200c Inhibits invasion, migration and proliferation of bladder cancer cells through down-regulation of BMI-1 and E2F3. J Transl Med. 2014;12:305. https://doi.org/10.1186/s12967-014-0305-z.

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  1. Laboratory of Urology, Guangdong Medical College, Zhanjiang, 524001, China

    Lei Liu, Mingning Qiu, Guobin Tan, Ziji Liang, Yue Qin, Lieqian Chen, Hege Chen & Jianjun Liu

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  1. Lei Liu
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  2. Mingning Qiu
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Correspondence to Hege Chen or Jianjun Liu.

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Liu, L., Qiu, M., Tan, G. et al. Correction to: miR-200c Inhibits invasion, migration and proliferation of bladder cancer cells through down-regulation of BMI-1 and E2F3. J Transl Med 20, 153 (2022). https://doi.org/10.1186/s12967-022-03299-6

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Journal of Translational Medicine

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