Fig. 1

Upregulation of PRMT5 in HCC tissues and its association with poor survival. A Immunohistochemical staining of PRMT5 in HCC tissues and corresponding NATs. Positive cells were stained brown. Magnification, (a, c) ×50; (b, d) ×100; scale bar 50 μm. B PRMT5 scores based on the nuclear or cytoplasmic levels of expression in 54 HCC patients, compared with matched normal tissues. C Association between PRMT5 expression and the survival of HCC patients