Fig. 8

pH connection to clinical outcome. a Association between low pH at the beginning of the manufacturing process and clinical response has been proven in 80% of the patients whereas only 20% of patients demonstrated clinical response when their cells were manufactured in higher pH. b Patients with high baseline disease burden which cells were kept at lower pH displayed higher probability of clinical response. c Patients who received previous hematopoietic stem cell transplant were associated with clinical responsiveness as long as the manufacturing process of their cells started with low pH