Fig. 5
From: Deciphering the importance of culture pH on CD22 CAR T-cells characteristics
pH related changes in cytokines and growth factors in cell culture supernatants from CD22 CAR T-cells at the harvest. Reduced levels of IL6 (p < 0.008), IL-12p70 (p < 0.003), TNF-a (p < 0.008), LIF (p < 0.007), MIF (p < 0.002), M-CSF (p < 0.003) and GM-CSF (p < 0.02) were found in cell supernatants with higher pH