Fig. 6

The ubiquitin–proteasome pathway was activated. A Transcription levels of ubiquitin and associated enzymes. B Transcription levels of proteasome components and Pomp. C Transcription levels of genes involved in the assembly of MHC-I and antigen peptide complexes. D UMAP plot depicting the single-cell activity of the “ubiquitin protein transferase regulator activity” pathway with the GSVA score. E UMAP plot depicting the single-cell activity of the “ubiquitin-mediated proteolysis” pathway with the GSVA score. F UMAP plot depicting the single-cell activity of the “proteasome” pathway with GSVA score