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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: CD137+ and regulatory T cells as independent prognostic factors of survival in advanced non-oncogene addicted NSCLC patients treated with immunotherapy as first-line

Fig. 5

PMN (Lox1+)-MDSCs correlated with response to ICIs in naïve patients. A Histograms showed the percentage of PMN(Lox1+)-MDSCs and M-MDSCs in 30 naïve NSCLC patients. Black histograms represented the values of these cells in responders (R) and gray histograms represented the PMN (Lox1+)-MDSCs and M-MDSCs values in non-responders (NR). B Histogram displayed the % PMN(Lox1+)-MDSCs/%CD137+ T cell ratio in R (black) and NR (grey) naïve patients; Kaplan–Meier curves for OS were used to determine 0.4% as the cut-off of % PMN(Lox1+)-MDSCs/%CD137+T cell ratio. m = months, p values < 0.05 were considered significant

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Journal of Translational Medicine

ISSN: 1479-5876

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