Fig. 7

Random forest analysis results. A Variable importance ranking of Model A +. B Variable importance ranking of Model B +. C Variable importance ranking of Model C +. D ROC curve of Model A +. E ROC curve of Model B +. F. ROC curve of Model C +. ROC receiver operating characteristic curve, AUC area under the curve, fT3 free triiodothyronine, fT4 free thyroxine, TSH thyroid stimulating hormone, TPOAb thyroid peroxidase autoantibody, TgAb thyroglobulin autoantibody, TRAb thyroid stimulating hormone receptor autoantibody, m month. Model A +: baseline predictive model for total group (N = 346). Model B +: combined model of high cumulative MMI dosage group (≥ 1730 mg, average ≥ 20 mg/day, N = 114) at 3 months of therapy. Model C +: combined model of medium–low cumulative MMI dosage group (< 1730 mg, average < 20 mg/day, N = 232) at 3 months of therapy