Fig. 1

The abundance of short-chain fatty acid (SCFA)-producing bacteria is markedly decreased in patients with active UC. A-B. Abundance of short-chain fatty acid (SCFA)-producing bacteria in patients with active Crohn’s disease (CD) (n = 52) and ulcerative colitis (UC) (n = 21) compared with healthy controls (n = 34) from the Inflammatory Bowel Disease Multi’omics Database. C. Correlation analysis between microbial abundance and inflammatory markers of UC (modified Baron’s score, C-reaction protein [CRP], and erythrocyte sedimentation rate [ESR]). D. Relative abundance of SCFA-producing bacteria in patients with active UC (n = 31) and healthy controls (HC) from Guangzhou First People’s Hospital (n = 6). *P < 0.05, **P < 0.01, ***P < 0.001 (Student’s t-test); ns, not significant