Fig. 9
QA improved TMAO-induced LDL trans-endocytosis of HCAECs through HMGB1/SREBP2. (A) CCK-8 was applied to detect the proliferation of HCAECs cells. (B-C) LDL uptake assay. Scale bar = 25 μm. (D-G) The expression of HMGB1, SREBP2, SR-BI and LDL-R was detected by RT-qPCR and western blot. *P < 0.05 vs. Control, #P < 0.05 vs. LDL, &P < 0.05 vs. LDL + TMAO