Fig. 2

QA improved inflammation and lipid levels in peripheral blood of Apoe−/− mice induced by HFD. (A-B) Peripheral blood TMAO and TMA levels were determined by non-targeted metabolism. (C-F) The TC, TG, HDL-C and LDL-C were tested by ELISA. (G) The CAV-1, ATP binding cassette transporter A1 (ABCA1), sterol regulatory element-binding protein-1 (SREBP-1) and liver-X-receptor (LXR) expression in the vascular tissues were analyzed by western blot. (H) ELISA was applied to analyze the CXCL13, TIMP-1 and HMGB1 levels. *P < 0.05 vs. NC, #P < 0.05 vs. HFD, &P < 0.05 vs. HFD + QA