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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Overexpression of TNFSF11 reduces GPX4 levels and increases sensitivity to ferroptosis inducers in lung adenocarcinoma

Fig. 6

TNFSF11 expression is negatively correlated with GPX4. (A) Heat map illustrating the relationship between TNFSF11 expression and antioxidative enzymes, namely CAT, SOD1, GPX1, and GPX4 (**P < 0.01, and ***P < 0.001). (B, C, E, F, G, H, J, K) Comparison of mRNA expression of TNFSF11 and GPX4 post lentiviral transduction in H2126 and PC-9 cells. Bars, means ± SD, n = 3. **P < 0.01, ***P < 0.001, NS, no significant. (D and I) Western blot analysis of CAT, SOD1, GPX4, and TNFSF11 expression post lentiviral transduction in H2126 and PC-9 cells. α-Tubulin was used as a loading control. All results were repeated for three times. CAT: Catalase

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