Fig. 6From: Overexpression of TNFSF11 reduces GPX4 levels and increases sensitivity to ferroptosis inducers in lung adenocarcinomaTNFSF11 expression is negatively correlated with GPX4. (A) Heat map illustrating the relationship between TNFSF11 expression and antioxidative enzymes, namely CAT, SOD1, GPX1, and GPX4 (**P < 0.01, and ***P < 0.001). (B, C, E, F, G, H, J, K) Comparison of mRNA expression of TNFSF11 and GPX4 post lentiviral transduction in H2126 and PC-9 cells. Bars, means ± SD, n = 3. **P < 0.01, ***P < 0.001, NS, no significant. (D and I) Western blot analysis of CAT, SOD1, GPX4, and TNFSF11 expression post lentiviral transduction in H2126 and PC-9 cells. α-Tubulin was used as a loading control. All results were repeated for three times. CAT: CatalaseBack to article page