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Table 7 Missense and frameshift mutations for which neo-epitopes have not been predicted in any of the 12 haplotypes considered in the study

From: Lack of shared neoantigens in prevalent mutations in cancer

MISSENSE

TOP FREQ

FRAMESHIFT

TOP FREQ

BCORN1459S

 

ACVR2AK437Rfs*5

Stomach

BRAFV640E/V600E

Colon, Skin, Thyroid

APCT1556Nfs*3

 

BRAFV640M

 

BCORL1P1681Qfs*20

 

ERBB2S310F

 

GLI1G274Afs*6

 

FBXW7R465C

 

JAK1K860Nfs*16

 

FBXW7R465H

 

JAK1P430Rfs*2

 

FBXW7R479Q

 

NPM1W317Cfs*12

 

FBXW7R505C

 

PTENK267Rfs*9

 

FBXW7R505G

 

PTENT319*

 

FGFR2S252W

 

RPL22K15Rfs*5

Corpus Uteri

FGFR3S249C

Bladder

SALL4V995Ffs*14

 

GNAQQ209P

 

ZMYM2K1044Rfs*33

 

HRASQ61R

Adrenal gland

  

IDH1R132C

   

IDH1R132H

Brain

  

KRASA146T

   

KRASG12A

   

KRASG12C

Lung

  

KRASG12D

Pancreas, Rectum

  

KRASG12R

   

KRASG12S

   

KRASG12V

   

KRASG13D

   

KRAS Q61H

   

NRASG12D

   

NRASG13D

   

NRASG13R

   

NRASQ61K

   

NRASQ61L

   

NRASQ61R

Hematopoietic

  

PIK3CAC420R

   

PIK3CAE542K

   

PIK3CAE545K

Cervix uteri, Larynx

  

PIK3CAH1047R

Breast

  

POLEP286R

   

PTENR130G

Uterus

  

PTENR130Q

   

TP53G245S

   

TP53H179R

   

TP53H193R

   

TP53I195T

   

TP53R175H

Ovary, Esophagus

  

TP53R248Q

   

TP53R248W

Bones

  

TP53R273C

   

TP53R273H

   

TP53R273L

   

TP53R282W

   

TP53V157F

   

TP53Y220C

   
  1. For those, which are reported as top frequent in a specific tumor, the tumor types are listed (TOP FREQ.)