Fig. 3

Mutation landscape analysis of MitoScore signature genes. Recurrent regions of copy number amplification and deletion in the A low and B high- MitoScore subgroup; C the Manhattan plot of copy number in high- (right) and low-(left) MitoScore subgroup; D correlation of frequency of arm-level events and number of genes on chromosome arm; E Top 15 mutated genes were illustrated in the low- (up)and high-(down) MitoScore signature; F the CNV frequency of each MitoScore signature genes; G The MitoScore of GC patients with microsatellite instability-high (MSI-H), microsatellite instability-low (MSI-L) and microsatellite stability (MSS); H Comparison of high- and low- MitoScore subgroups of TMB; I MitoScore and TMB-categorized OS Kaplan–Meier curves