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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Focused ultrasound-mediated blood–brain barrier opening is safe and feasible with moderately hypofractionated radiotherapy for brainstem diffuse midline glioma

Fig. 6

Disease progression kinetics and survival. a Representative T2-weighted MRI of RT and RT + FUS mice taken 37, 44, and 51 days following intracranial implantation, with red arrows and outlines indicating tumor presence. b Quantitative analysis of the tumor volume of T2-weighted MRI. Values are means ± SEM. NS indicates non-significant (P > 0.05) in two-way ANOVA. c Survival analysis. The Kaplan–Meier curve shows the survival of control (black, n = 6), RT (blue, n = 9), and RT + FUS (green, n = 7) animals. *** indicates P < 0.001 and NS indicates non-significant (P > 0.05) using log-rank (Mantel-Cox) test

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