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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Low-intensity pulsed ultrasound delays the progression of osteoarthritis by regulating the YAP–RIPK1–NF-κB axis and influencing autophagy

Fig. 8

LIPUS inhibits cartilage degeneration in post-traumatic OA of rats. A Schematic diagram of animal experiment. B The body weight of rats. C H&E staining and Safranin O/Fast green of the six groups (scale bar: 500 μm). D Immunohistochemistry staining to show the COL2A1-positive cell, MMP13-positive cell and P62 -positive cell in cartilage of the six groups (scale bar: 100 μm). E The CT 3D reconstruction images of rats (scale bar: 1 mm). F Quantification of the estimation about mechanical and heat pain. G Serum concentration quantification of IL-1β and TNF-α. Data are shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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