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Table 2 Cox multivariable-regression analyses of overall survival in relation to COMP expression in stroma and cancer cells

From: Stromal cartilage oligomeric matrix protein as a tumorigenic driver in ovarian cancer via Notch3 signaling and epithelial-to-mesenchymal transition

Overall Survival

Stroma

Cancer cells

Variable

HR

95% CI

p-value

HR

95% CI

p-value

COMP (Weak vs strong)

2.03

1.33–3.10

 < 0.001

1.03

0.63–1.70

0.906

Subtype (Non-Serous vs Serous)

1.39

0.90–2.15

0.140

1.47

0.95–2.28

0.086

Grade (1–2 vs 3)

0.63

0.39–1.01

0.053

0.66

0.41–1.05

0.082

FIGO stage (I-II vs III-IV)

2.51

1.52–4.13

 < 0.001

2.63

1.58–4.37

 < 0.001

Ki67 (0–10% vs 11–25% vs > 25%)

1.06

0.81–1.38

0.683

1.07

0.81–1.41

0.645

  1. Bold values indicate p-values < 0.05
  2. COMP: cartilage oligomeric matrix protein, FIGO: Federation Internationale de Gynecolgie et d'Obstetrique
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Journal of Translational Medicine

ISSN: 1479-5876

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