Fig. 6

The proportion of T cell subsets in PI16^CKO and PI16^fl/fl DSS-induced colitis model. A–D The expression level of Th1 (A, 3.42 ± 0.19% vs. 6.59 ± 1.28%, p = 0.028), Th2 (B, 1.52 ± 0.27% vs. 2.76 ± 0.38%, p = 0.018), Th17 (C, 2.18 ± 0.55% vs. 6.42 ± 1.47%, p = 0.017), and Treg (D, 1.40 ± 0.15% vs. 0.50 ± 0.11%, p = 0.003) in DSS-induced colitis model mice; E, F Th17/Treg balance (E, 1.44 ± 0.50% vs. 24.09 ± 7.18%, p = 0.012) and Th1/Th2 balance (E, p > 0.05) in DSS-induced colitis model mice. (PI16^CKO DSS = 8, PI16^fl/fl DSS = 8, PI16^CKO NC = 7, PI16^fl/fl NC = 7) *p < 0.05, **p < 0.01, ***p < 0.001