Fig. 3
The amino acid composition feature of oxidized peptides in pancreatic cancer cells. A The amino acid frequencies of 20 positions flanking cysteine oxidation sites in HPDE6c7 and PANC-1 cells. Animo acid frequencies based on all oxidation peptides identified in this study were analyzed by the MoMo software. High and low amino acid frequencies were indicated by red and green colors, respectively. Significant overrepresentation of amino acids was marked by red arrows. B Consensus sequences of protein cysteine oxidation in HPDE6c7 and PANC-1 cells. Statistically significant motifs for protein cysteine oxidation were extracted from all identified oxidation peptides using the Motif-X algorithm