Mean after 120 min | Linear mixed model | |||||
---|---|---|---|---|---|---|
Control | Lactate | Change compared with control | 95% CI | P-value | P-value for interaction | |
pH | 7.50 ± 0.11 | 7.60 ± 0.06 | 0.22 | 0.20 to 0.24 | < 0.001 | 0.007 |
HCO3− (mmol/L) | 36 ± 9 | 47 ± 5 | 21 | 19 to 22 | < 0.001 | < 0.001 |
Potassium (mmol/L) | 3.7 ± 0.49 | 3.6 ± 0.69 | -0.97 | -1.30 to -0.65 | < 0.001 | 0.15 |
Natrium (mmol/L) | 160 ± 6 | 158 ± 8 | -3.6 | -4.8 to -2.4 | < 0.001 | 0.4 |
Strong ion difference (mmol/L) | 49.0 ± 8.2 | 59.0 ± 2.6 | 19.0 | 17.0 to 21.0 | < 0.001 | < 0.001 |
Hgb (mmol/L) | 5.90 ± 0.90 | 5.90 ± 0.42 | 0.10 | -0.22 to 0.42 | 0.5 | 0.5 |
Glucose (mmol/L) | 5.20 ± 1.30 | 6.20 ± 1.00 | 1.60 | 0.52 to 2.70 | 0.007 | 0.4 |
Lactate (mmol/L) | 0.79 ± 0.24 | 9.60 ± 1.40 | 9.9 | 9.1 to 11.0 | < 0.001 | 0.2 |
FFA (mmol/L) | 0.40 ± 0.25 | 0.45 ± 0.36 | 0.12 | -0.28 to 0.52 | 0.6 | 0.5 |
Osmolarity (mmol/L) | 330 ± 13 | 326 ± 15 | -5.6 | -8.2 to -3.0 | < 0.001 | 0.6 |
Insulin (mU/L) | 1.0 ± 0.4 | 3.5 ± 2.0 | 3.2 | 1.6 to 4.8 | < 0.001 | > 0.9 |
3-hydroxybutyrate (µmol/L) | 6.6 ± 4.5 | 5.8 ± 6.0 | -1.5 | -6.0 to 3.1 | 0.5 | 0.9 |
Diuresis (mL) | 138 ± 189 | 107 ± 75 | 18 | -176 to 212 | 0.9 | 0.082 |