Table 1 Baseline features of 294 HBV-infected patients enrolled in this study and stratification analyses [Median (Min–Max)]

1

R

13

34 (24–57)

10/3

83 (25–281)

23.9 (11.5–143.8)

 < 2.69 (< 2.69–7.41)

 < 0.05 (< 0.05)

110.4 (2–704.5)

0.104 (0.081–1.71)

0.021 (0.002–3.47)

0.007 (0.006–0.009)

2

CHB

203

37 (16–71)

147/56

46 (0–622)

29.15 (8.2–391.2)

 < 2.69 (< 2.69–8.69)

1374.5 (0.05–52000)

2 (0.52–608.3)

2.51 (0.072–1726)

0.621 (0.002–30.56)

0.007 (0.006–8.44)

3

LC

52

49 (29–72)

41/11

49 (0–285)

30.2 (5.6–295.7)

 < 2.69 (< 2.69–3.41)

763.4 (0.2–6487)

2 (2–4.5)

1.16 (0.058–725.6)

0.267 (0.003–3.02)

0.007 (0.006–0.008)

4

HCC

26

54 (25–68)

20/6

93 (0–406)

33.1 (9–214.5)

2.69 (< 2.69–4.415)

212.665 (5.82–2621)

2 (2–35)

0.1125 (0.057–5.43)

0.883 (0.002–1.27)

0.007 (0.006–0.008)

P^a

p = 0.0099

p < 0.0001

p < 0.0001

p = 0.0037

p = 0.0006

P^b

R versus CHB

p = 0.012

p < 0.0001

p < 0.0001

p = 0.028

p = 0.0021

R versus LC

p = 0.014

p < 0.0001

p = 0.00042

p = 0.0024

CHB versus HCC

p = 0.026

p = 0.0053

p = 0.0022

p = 0.0022

R versus HCC

p < 0.0001

LC versus HCC

p = 0.032

P^c

p = 0.04

p = 0.019

p = 0.003