Fig. 2

Association of HBV-specific T cell reactivity with sero-virological parameters in CHB patients. A Stratified analyses of HBV-specific T cells (SFUs) in CHB patients grouped by HBV DNA load (< 3.0, n = 70; 3.0–5.0, n = 27; > 5.0, n = 23), HBsAg level (< 1000, n = 82; 1000–10000, n = 64; > 10,000, n = 34), HBeAg level (< 1, n = 53; 1–100, n = 45; 100–1000, n = 13; > 1000, n = 15) and ALT level (< 40, n = 146; > 40, n = 56). B Stratified analyses of sero-virological parameters in CHB patients grouped by HBV-specific T cell reactivity (0–24 SFUs for 25% of the cohort; 25–90 SFUs for 50% of the cohort; 91–622 SFUs for 25% of the cohort). For HBV DNA load, HBsAg level, HBeAg level, and ALT level analyses, 0–24 group, n = 42, 27, 41, 50, respectively; 25–90 group, n = 93, 59, 77,101, respectively; 91–622 group, n = 45, 24, 52, 51, respectively. C Spearman correlation tests between HBV-specific T cells (SFUs) and HBV DNA, HBsAg, HBeAg or ALT levels