EBV−(n = 201) | EBV + (n = 48) | P value | |
---|---|---|---|
Patients age, median(range) | 26 (1–64) | 29.5 (1–66) | 0.339 |
Donors age, median(range) | 37.5 (9–65) | 42 (9–65) | 0.012 |
Patients gender, n(%) | 0.060 | ||
Male | 117 | 35 | |
Female | 84 | 13 | |
Donors gender, n(%) | 0.178 | ||
Male | 153 | 32 | |
Female | 48 | 16 | |
ABO type, n(%) | 0.016 | ||
Match | 95 | 32 | |
Mismatch | 106 | 16 | |
Donor-recipient relationship, n(%) | 0.336 | ||
Patrents to children | 118 | 33 | |
Children to parents | 46 | 10 | |
Sibling | 37 | 5 | |
Donor-recipient gender, n(%) | 0.004 | ||
Female to male | 25 | 14 | |
Others | 176 | 34 | |
Stem cell source, n(%) | 0.106 | ||
BM + PB | 34 | 13 | |
PB | 167 | 35 | |
Serological EBV status of patients and donors, n(%) | 0.588 | ||
P−D− | 1 | 0 | |
P−D + | 8 | 0 | |
P + D− | 8 | 1 | |
P + D + | 184 | 47 | |
HLA mismatch, n(%) | 0.405 | ||
1 | 14 | 1 | |
2 | 22 | 7 | |
3 | 165 | 40 | |
aGVHD, n(%) | 0.331 | ||
aGVHD− | 123 | 27 | |
aGVHD grade 1–2 | 68 | 16 | |
aGVHD grade 3–4 | 10 | 5 | |
Count of grafts components/kg, median(range) | |||
MNC (108/kg) | 9.29 (5.01–20.25) | 10.27 (5.3–19.15) | 0.028 |
CD34 (106/kg) | 3.42 (0.67–17.64) | 3.39 (1.28–13.09) | 0.575 |
Lym (106/kg) | 370.30 (91.28–960.46) | 385.54 (151.18–640.10) | 0.666 |
CD14 (106/kg) | 157.82 (55.11–348.05) | 155.32 (84.31–360.26) | 0.369 |
CD3 (106/kg) | 255.03 (64.62–650.48) | 254.01 (74.32–496.17) | 0.585 |
CD4 (106/kg) | 139.65 (38.39–414.48) | 141.61 (43.69–331.41) | 0.846 |
CD8 (106/kg) | 89.05 (20.17–277.85) | 84.95 (24.87–206.48) | 0.138 |
NK (106/kg) | 35.96 (6.09–183.20) | 30.28 (7.27–107.07) | 0.347 |