Fig. 7
From: CDC45 promotes the stemness and metastasis in lung adenocarcinoma by affecting the cell cycle
Knockdown of CDC45 inhibits EMT in H1299 and A549 cells. A, B Representative pictures and quantitative analysis of the inhibitory effect of CDC45 knock-down on cell invasion in A549 cells. C, D In H1299 cells, the representative pictures and quantitative analysis of the inhibitory effect of CDC45 knock-down on cell invasion. E, F Western blot assay, after knockdown CDC45, expression levels in Vimentin, E-cadherin, and N-cadherin in A549 and H1299 cells decreased, while knockdown CDC45 reduced levels of MMP2 and MMP9, with the reference proteinβ-actin used as an internal control