Fig. 6

Correlations between HIF-1α and TGF-β1 in model cells and human tissues. a mRNA expression correlation between HIF-1α and TGF-β1 in the CCLE database. Left: all cells. Right: Subgroups of cells cultured in low-glucose culture medium or high-glucose culture medium. (https://sites.broadinstitute.org/ccle/). b Overview of the correlation between HIF-1α and TGF-β1 mRNA expression in tissues with higher glucose demand or lower glucose demand. The data were sourced from the GTEx database. (https://www.gtexportal.org/). c Correlations of HIF-1α and TGF-β1 expression in various tissues: the esophagus, adipose tissue, skin, brain, heart, and liver. d The correlation analysis between the indicated gene sets in GSE125498. e Positive correlation between HIF-1α and TGF-beta pathway in GSE125498