Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction

Table 2 Dysregulated exosomal circRNAs derived from plasma of IPF patients and control volunteers with fold change (FC) > 2 and p < 0.05

circRNA	Alias	circRNA_type	Gene symbol	position (genome browser link)	strand	FC(IPF vs non-IPF)	p
hsa_circRNA_102100	hsa_circ_0044226	Exonic	CDC27	chr17:45214517–45221348	−	2.644272	0.006303
hsa_circRNA_100759	hsa_circ_0004099	Exonic	DENND5A	chr11:9225206–9229179	−	2.43274	0.002181
hsa_circRNA_100705	hsa_circ_0008898	Exonic	OAT	chr10:126097110–126100769	−	2.409697	0.001874
hsa_circRNA_101550	hsa_circ_0035796	Exonic	HERC1	chr15:63988322–64008672	−	2.30596	0.043317
hsa_circRNA_102348	hsa_circ_0007535	Exonic	ELP2	chr18:33722243–33739978	+	2.135311	0.01038
hsa_circRNA_102101	hsa_circ_0044234	Exonic	CDC27	chr17:45247282–45249430	−	2.109072	0.033608
hsa_circRNA_102470	hsa_circ_0049888	Exonic	EPS15L1	chr19:16547747–16548676	−	0.454531	0.026483
hsa_circRNA_101192	hsa_circ_0005465	Exonic	CLIP1	chr12:122861935–122865105	−	0.448258	0.020135
hsa_circRNA_104780	hsa_circ_0001861	Exonic	GRHPR	chr9:37424841–37426651	+	0.412857	0.004532
hsa_circRNA_101225	hsa_circ_0029633	Exonic	ZMYM2	chr13:20625572–20641530	+	0.392345	0.000636
hsa_circRNA_102049	hsa_circ_0043278	Exonic	TADA2A	chr17:35797838–35800763	+	0.24053	0.011284

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