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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Exosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction

Fig. 8

The biological function of hsa_circ_0044226. A The expression level of hsa_circ_0044226 in HFL1 cells treated with TGFβ1, TGFβ1 plus scramble RNA (TGFβ1 + NC) or TGFβ1 plus hsa_circ_0044226 siRNA (TGFβ1 + siRNA). B–E The protein levels of α-SMA, FN and COL1 in HFL1 cells treated with TGFβ1, TGFβ1 plus scramble RNA (TGFβ1 + NC) or TGFβ1 plus hsa_circ_0044226 siRNA (TGFβ1 + siRNA). B Represent image; C–E statistic value of α-SMA, FN and COL1. F the proliferation ability of HFL1 cells treated with TGFβ1, TGFβ1 plus scramble RNA (TGFβ1 + NC) or TGFβ1 plus hsa_circ_0044226 siRNA (TGFβ1 + siRNA). CTL: HFL1 cells treated without TGFβ1. Each test was repeated three times. The mean differences were analyzed by Student’s t test. *P < 0.5;**P < 0.01;***P < 0.001

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