Fig. 2

Longitudinal dynamics of human gut microbiota and SFCA in the control group. a Alpha diversity of control group gut microbiota over time. b PCoA analysis of control group gut microbiota at each time point. c Tracing the OTUs at each time point. Fecal samples of the former time point were taken as potential sources of the latter time point. The bands of each color indicate the different phylum. d The temporal changes of bacterial abundance at the phylum level and different time points. The significant points represent the changes from Pre. e Clustering of the gut microbiota at the genus level and different time points, a log10 transformation was performed on the OTU. f Significantly different genera at each time point, compared to the Pre time point with a p-value < 0.05 (using Wilcoxon rank-sum test), are shown. Colour in the heatmap represent z-values obtained from the Wilcoxon rank sum test. g The changes of SCFAs in fecal samples, normalized to Pre. *p < 0.05, **p < 0.01