Table 3 Summary of findings from studies included in the meta-analysis and meta-regression
From: Cell therapy for retinal degenerative disorders: a systematic review and three-level meta-analysis
Study | Subgroup | No. Studies | No. eyes | Meta-analysis | Meta-regression | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Standardized MD | 95%CI | P-value | Subgroup difference | Variable | estimate | P-value |
AMD | Wet | 2 | 5 | − 1.74 | − 2.91 to − 0.58 |  < 0.01 |  < 0.05 | Publication year | 0.35 |  < 0.05 |
Mean age | 0.30 |  < 0.0001 | ||||||||
Dry | 10 | 135 | − 0.26 | − 0.73–0.22 |  < 0.01 | Scaffold | − 3.50 |  < 0.001 | ||
RPE | 1.90 |  < 0.0001 | ||||||||
NSC | − 1.97 |  < 0.05 | ||||||||
Overall | 12 | 140 | − 0.47 | − 0.91 to − 0.03 |  < 0.05 | |||||
BMSC | 0.50 | 0.17 | ||||||||
UPMSC | − 1.16 | 0.11 | ||||||||
SMD | Overall | 2 | 40 | 0.25 | − 0.52–1.02 | 0.52 | NA | Publication year | − 0.01 | 0.74 |
Mean age | − 0.03 |  < 0.05 | ||||||||
RPE | 1.38 | 0.09 | ||||||||
BMSC | 1.24 | 0.15 | ||||||||
RP | Overall | 2 | 44 | 0.41 | 0.16–0.67 |  < 0.01 | NA | NA | NA | NA |