Gene | Measured time | OS ≥ 6 months | OS ≥ 12 months | PFS ≥ 6 months | PFS ≥ 12 months | PR as BORa | PD as BORa |
---|---|---|---|---|---|---|---|
P value | P value | P value | P value | P value | P value | ||
KRAS | 2 | 0.001 | 0.026 | 0.021 | 0.178 | 0.344 | 0.012 |
 | 3 | 0.014 | 0.002 | 0.002 | 0.057 | 0.315 | 0.681 |
TP53 | 2 | < 0.001 | 0.083 | 0.059 | 0.151 | 0.108 | 0.015 |
 | 3 | 0.001 | 0.149 | 0.098 | 0.184 | 0.044 | 0.164 |
CDKN2A | 2 | 0.027 | 0.027 | 0.004 | 0.465 | 0.202 | NE |
 | 3 | 0.031 | 0.031 | 0.002 | 0.439 | 0.176 | NE |