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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling

Fig. 7

Overexpression of SP1 promotes RBBP7 proliferation and glycolysis in HCC in vitro. Compared with oeSP1 + shNC group #, P < 0.05; ##, P < 0.01; ###, P < 0.001; ####, P < 0.0001. Compared with oeSP1 + shRBBP7-2 group *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. A–C. RBBP7 expression was test by western blotting and RT-qPCR in SP1 rescue experiments. D. CCK-8 assay was employed to examine cell growth in the SP1 rescue experiment. E, F. Colony formation assay was performed in the SP1 rescue experiment. G. ATP concentration in the SP1 rescue experiment. H. Lactic acid concentration in the SP1 rescue experiment. I. Glucose uptake capacity in the SP1 rescue experiment. J. NAD+/NADH colorimetric assay in the SP1 rescue experiment

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Journal of Translational Medicine

ISSN: 1479-5876

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