Fig.1From: Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer seriesA classical MSI-high colorectal cancer case with MLH1/PMS2 losses. A. Loss of MLH1 protein from tumor cells while normal cells remained positive. B. Matching area. Loss of PMS2 protein from tumor cells. Bars = 200 µm. C/D. Pentaplex analysis of the case. Tumor proportion: 50%. C. Control K562 tumor cell line with all five stable markers. D. Tumor sample. Note the aberrant markers BAT-25, Mono27, NR21 and NR24 (red arrows) in the cancer caseBack to article page