Fig. 7

Inhibition of IMPDH2 reversed oxaliplatin resistance in vivo. A Tumour images. B Tumour growth curve. C Tumour weight. D Body weight. E The H&E and IHC of Ki-67 of tumour tissue with indicated treatment. F A schematic diagram of the Wnt/β‑catenin/IMPDH2 mediated purine metabolism regulating oxaliplatin-induced apoptosis in CRC. ns, not significant, *p < 0.05, **p < 0.01, and ***p < 0.001