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Table 3 Analysis of markers specific to inflammatory and immune cells from bronchoalveolar lavage (BAL) fluid by flow cytometry

From: The siRNA-mediated knockdown of AP-1 restores the function of the pulmonary artery and the right ventricle by reducing perivascular and interstitial fibrosis and key molecular players in cardiopulmonary disease

Markers

C group

(n = 5)

MCT group

(n = 5)

MCT-siRNA AP-1 group (n = 5)

MHC-II

2.68 ± 1.28

4.03 ± 0.81

5.96 ± 1.89

**P < 0.01

CD11c

66.16 ± 2.89

75.63 ± 5.98

75.96 ± 3.05

CD3e

55.88 ± 3.80

64.47 ± 10.69

73.54 ± 2.38

Singlec-1

63.63 ± 5.43

76.10 ± 9.09

75.93 ± 1.91

CD4

54.84 ± 18.19

75.99 ± 4.88

***P < 0.005

73.74 ± 2.42

**P < 0.01

CD8

1.69 ± 1.34

9.98 ± 4.24

***P < 0.005

7.05 ± 1.14

**P < 0.01

  1. Five individual experiments were made for each experimental group. The data represent the means ± SD
  2. Statistical significance represented as ***P < 0.005, **P < 0.01 values versus control group. One-way ANOVA, Bonferroni post-test was applied