Fig. 7

Analysis of plasma inflammatory cytokines at 4 and 12 experimental weeks: A ET-1, B TGF-β1, C IL-1β and D TNF-α levels evaluated by enzyme-linked immunosorbent assay (ELISA) method, for all three experimental groups: C, MCT, MCT-siRNA AP-1. The measurements were performed in triplicate and results were depicted as mean ± SD. The statistical significance, noticeably different, was represented as ***P < 0.005, *P < 0.05 versus control group and ^###P < 0.005, ^##P < 0.01, ^#P < 0.05 versus MCT group. The values were calculated by One-way ANOVA, Bonferroni post-test