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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: The siRNA-mediated knockdown of AP-1 restores the function of the pulmonary artery and the right ventricle by reducing perivascular and interstitial fibrosis and key molecular players in cardiopulmonary disease

Fig. 4Fig. 4Fig. 4

Changes in the blood flow, structure and function of pulmonary artery and right ventricle for the investigated experimental groups: C, MCT, MCT-siRNA AP-1. A Representative recordings obtained in pulsed wave Doppler-mode, which highlight the Velocity Time Integral (VTI, mm) and Doppler Peak Velocity (Vel, mm/s) of the pulmonary artery; B representative B-mode recordings, which highlight the inner diameter (mm) of the pulmonary artery; C Representative B-mode recordings, which highlight the area of the right and left ventricle in diastole (mm2); D Representative M-mode recordings, which highlight right ventricle wall thickness in diastole (RVWTd, mm); Representative M-mode recordings, which highlight proximal ventricle outflow chamber during systole and diastole (PRVOFd, PRVOFs, mm); E Representative M-mode recordings which highlight tricuspid annular plane systolic excursion (TAPSE, mm)

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