Fig. 3From: The siRNA-mediated knockdown of AP-1 restores the function of the pulmonary artery and the right ventricle by reducing perivascular and interstitial fibrosis and key molecular players in cardiopulmonary diseaseA Representative images with myographic recordings at selected time points: for the contraction at NA (10−8 M ÷ 10−4 M) and relaxation at ACh (10−8 M ÷ 10−4 M) of the pulmonary arteries isolated from all three investigated experimental groups. Images were recorded with LabChart 7 software. B Measures of maximal contraction forces developed by pulmonary arteries to 10–4 M NA and maximal relaxation percentages to 10–4 M ACh for the three hamster groups. Data are means ± SD of 4 independent experiments for each investigated group. The statistical significance, noticeably different, was represented as ***P < 0.005, *P < 0.05 versus control group and ##P < 0.01 versus MCT group. Probability values were calculated by One-way ANOVA, Bonferroni post-testBack to article page