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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The siRNA-mediated knockdown of AP-1 restores the function of the pulmonary artery and the right ventricle by reducing perivascular and interstitial fibrosis and key molecular players in cardiopulmonary disease

Fig. 3

A Representative images with myographic recordings at selected time points: for the contraction at NA (10−8 M ÷ 10−4 M) and relaxation at ACh (10−8 M ÷ 10−4 M) of the pulmonary arteries isolated from all three investigated experimental groups. Images were recorded with LabChart 7 software. B Measures of maximal contraction forces developed by pulmonary arteries to 10–4 M NA and maximal relaxation percentages to 10–4 M ACh for the three hamster groups. Data are means ± SD of 4 independent experiments for each investigated group. The statistical significance, noticeably different, was represented as ***P < 0.005, *P < 0.05 versus control group and ##P < 0.01 versus MCT group. Probability values were calculated by One-way ANOVA, Bonferroni post-test

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