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Table 3 Hazard ratios of demographic and clinical parameters obtained by log-rank test

From: Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian population

Characteristic

HR

95% CI

p-value

Age

1.7413

0.8202 to 3.6965

0.150

Sex

1.5123

0.7092 to 3.2250

0.280

Surgery

0.05810

0.01923 to 0.1755

 < 0.0001

Adjuvant therapy

0.3638

0.1639 to 0.8076

0.013

Neo-adjuvant therapy

0.8056

0.3563 to 1.8213

0.600

First-line therapy

0.8185

0.3568 to 1.8773

0.630

T (T3-4 vs T1-2) stage

9.5881

1.4152 to 64.962

0.026

N (N2 vs N1) stage

2.3826

0.9539 to 5.9511

0.063

M stage (M1 vs M0)

266

28 to 2563

 < 0.0001

  1. In bold, significant values
  2. HR, hazard ratio; CI, confidence interval