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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer

Fig. 1

Cancer testis antigen (CTA) co-expression in the discovery cohort. A Correlation plot detailing the pairwise Pearson correlations of 17 CTAs. All statistically significant (p ≤ 0.05) correlations are denoted, and an “X” indicates a nonsignificant correlation. The black rectangles are visual aids indicating the four observed groups of CTA expression, and the colors of the gene labels on both axes are additional visual aids to reflect these groups. B Network graph of CTA co-expression in the discovery cohort where the thickness and length of each edge represent the absolute value of the correlation between two CTA (a thick, short edge denotes a strong correlation and a thin, long edge denotes a weak correlation) and the color of each edge represents the direction of each observed correlation (a red edge represents a positive correlation and a blue edge represents a negative correlation). Note that edges are only shown for significant (p ≤ 0.05) correlations. The color of each node matches the axis gene labels on the correlation plot (a) and correspond to the main groups of CTA expression

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