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Table 1 The demographics of patients

From: The gut microbiota participates in the effect of linaclotide in patients with irritable bowel syndrome with constipation (IBS-C): a multicenter, prospective, pre-post study

  

Total (N = 60)

Non-relief (n = 9)

Relief (n = 51)

P value

Gender (n,%)

Female

52 (86.7)

9 (100)

43 (84.31)

0.024

 

Male

8 (13.3)

0 (0)

8 (15.69)

 

Age

Median (P25-P75)

47 (36.5 – 51.75)

40 (33 – 50.5)

47 (38 – 53)

0.722

 

Mean ± SD

45.2 ± 10.97

42.89 ± 10.96

45.61 ± 11.16

 

BMI

Median (P25-P75)

22.48 (21.26 – 23.99)

21.78 (18.598 – 23.05)

22.58 (21.34 – 24.28)

0.100

 

Mean ± SD

22.62 ± 2.76

20.94 ± 3.3

22.92 ± 2.75

 

Education

Primary

6 (10)

0 (0)

6 (11.76)

0.495

 

Medium

32 (53.3)

7 (77.78)

25 (49.02)

 
 

Higher

22 (36.7)

2 (22.22)

20 (39.22)

 

IBS-SSS

Median (P25-P75)

225 (156.25 – 275)

225 (162.5 – 342.5)

225 (125 – 275)

0.445

(Baseline)

Mean ± SD

225.17 ± 92.296

245.56 ± 86.05

221.57 ± 86.89

 

Basic disease *

No

56 (93.3)

9 (100)

47 (92.16)

0.347

 

Yes

4 (6.7)

0 (0)

4 (7.84)

 

Drug-related

side effects #

No

44 (73.3)

8 (88.89)

36 (70.59)

0.360

Yes

16 (26.7)

1 (11.11)

15 (29.41)

 
  1. BMI body mass index, IBS-SSS irritable bowel syndrome symptom severity scale
  2. *4 reported hypertension; # 16 reported diarrhea