Fig. 8
The FBXW7/CHD4/Wnt/β-catenin axis regulates the stem cell-like properties of TNBC cells. A Enrichment plots from GSEA to examine the correlation between CHD4 expression and multiple stemness-related gene sets based on TCGA-BRCA-TNBC datasets. B Heatmap analysis of the correlation between CHD4 expression and multiple stemness-related genes based on TCGA-BRCA-TNBC datasets. C ALDEFLUOR assay of the percentage of ALDH-positive cells in different treatment groups. D FACS profiles and quantification of the CD44high/CD24low subpopulation in different treatment groups