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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition

Fig. 4

CHD4 is a binding partner of FBXW7. A Venn diagram showing the number of overlapping genes between the four datasets as indicated. B Intracellular localization analysis of FBXW7 and CHD4 by immunofluorescence assay. The intracellular localization of CHD4 (red) and FBXW7 (green) is shown. Nuclei (blue) were stained with 4′,6-diamidino-2-phenylindole (DAPI). C Co-IP assays and Western blotting were conducted to detect the relationship between CHD4 and FBXW7. D A GST pull-down assay and Western blotting were performed to determine the interaction between FBXW7 and CHD4

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Journal of Translational Medicine

ISSN: 1479-5876

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