Fig. 2
From: Pharmacological and cell-based treatments to increase local skin flap viability in animal models
Cell-based therapies require the harvest of cells from relevant tissue type and processing prior to usage as a therapy for skin flaps. The most common sources of these cells are adipose tissue, bone marrow, placental amniotic membrane, and the umbilical cord. These cells are typically applied to preclinical murine models via subcutaneous injection, as depicted in a McFarlane flap