Fig. 7

Ddx41 knockdown suppresses IFN-I and inflammatory responses in BV2 cells treated with MPP⁺ conditioned media. A–E Ifnb1 (A), Irf7 (B), Il6 (C), Il1b (D) and Tnf (E) mRNA expression in BV2 cells transfected with Ddx41 siRNA and stimulated with or without MPP⁺-CM is shown by qPCR analysis. N = 3 per group. F, G DDX41 and IL-1β protein levels in BV2 cells transfected with Ddx41 siRNA and stimulated with or without MPP⁺-CM by western blot (F) and quantitative analysis (G) are shown. N = 3 per group. Data are shown as the mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001