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Fig. 9 | Journal of Translational Medicine

Fig. 9

From: (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease

Fig. 9

ALA reverses the effect of palmitic and oleic acid on senescence in HepG2 cells. A β-galactosidase, B, C γ-H2AX and D Klotho-Beta. Values represent the mean ± SD of experiments performed in quadruplicate. * vs CTRL (**p < 0.01, ***p < 0.001, ****p < 0.0001); § vs PA:OA (§§p < 0.01, §§§§p < 0.0001). Scale bars in B 50 μm

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