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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease

Fig. 5

ALA decreases mitochondrial membrane potential following PA:OA treatment. Cytofluorimetric analysis of mitoSox and DiOC2 following 6 h of ALA treatment. A Quantification of % of mitoROS formation following 6 h of treatment. B Representative plots of mitochondrial depolarization following 6 h of treatment. C Quantification of % depolarization. Values represent the mean ± SD of experiments performed in quadruplicate. * vs CTRL (**p < 0.01, ***p < 0.001, ****p < 0.0001); § vs PA:OA (§§p < 0.01, §§§p < 0.001)

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