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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Fucoidan modulates SIRT1 and NLRP3 to alleviate hypertensive retinopathy: in vivo and in vitro insights

Fig. 8

A working model of the mechanism by SIRT1/NLRP3 in Ang II-induced hypertensive retinopathy. Ang II infusion induced hypertensive retinopathy, ROS production, SIRT1 reduction and NLRP3 inflammasome activation. FO could rescue those reactions. SIRT1/NLRP3 might by a new sight of hypertensive retinopathy and dysfunction and FO might be used as an agent to protect against Ang II-induced hypertensive retinopathy

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Journal of Translational Medicine

ISSN: 1479-5876

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