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Table 1 Statistical methods and machine learning techniques are used in pregnancy literature

From: Molecular epidemiology of pregnancy using omics data: advances, success stories, and challenges

Statistical methods

Studies

T-test

Preeclampsia [15, 17, 22, 24, 30] | Metabolic syndrome [46] | Gestational diabetes[27, 48]

Placental abruption [20] | Fetal growth restriction [23] | Asthma in offspring [56]

Alternations of breastmilk components of COVID-19 [51]

Fisher's Exact Test

Preeclampsia [21, 22, 24, 30] | Fetal growth restriction [25] | Gestational diabetes [26]

Preterm delivery [29] | Alternations of breastmilk components of COVID-19 [51]

Asthma in offspring [54, 56]

Mann Whitney Rank Sum Test

Preeclampsia [17, 21, 28, 30] | Obesity and overweight [45] | Fetal growth restriction [25]

Gestational diabetes [26] | Preterm delivery [29]

Chi-squared test (include Wald test)

Preeclampsia [13, 24, 30] | Placental abruption [20] | Preterm delivery [29]

Asthma in offspring [53, 54]

ANOVA

Preeclampsia [13, 22, 28, 30] | Placental abruption [18] | Metabolic syndrome [46]

Asthma in offspring [53]

ROC analysis

Placental abruption [20] | Preeclampsia [21, 22, 28] | Gestational diabetes [26, 27]

Preterm delivery [29]

Logistic regression model (including Hosmer–Lemeshow Goodness-of-Fit Test)

Placental abruption [18, 20] | Gestational diabetes [26] | Asthma in offspring [53, 56]

Spearman rank correlations

Preeclampsia [24, 28] | Metabolic syndrome [46]

Post hoc analyses

Respiratory syncytial virus [4] | Preeclampsia [22, 30] | Asthma in offspring [53]

Linear regression model (including mixed effect model)

Maternal cardiovascular adaptation [3] | Preeclampsia [24] | Asthma in offspring [54]

Kaplan–Meier curve

Asthma in offspring [53, 54]

Kolmogorov–Smirnov test

Preeclampsia [22] | Gestational diabetes [27]

Principal component analysis (PCA)

Preeclampsia [13] | Metabolic dynamics of timing of delivery [19]

Cox regression

Asthma in offspring [53, 54]

Pearson correlation coefficient

Obesity and overweight [45]