Fig. 5

RM-RM is correlated with the mutation and tumor microenvironment characteristics of BLCA. A The top 20 mutated genes in different risk subgroups of TCGA BLCA were sorted according to the mutation rate. The color coding represents the mutation type. The total number of mutations is shown above, the percentage of mutations is shown on the right, and the distribution of base mutation types is shown below. B The top 10 genes with significant differences in mutant genes between the high- and low-risk subgroups. C Comparison of the immune, stromal and microenvironment scores in different risk subgroups. D Tumor microenvironment (TME) cells with significant differences in different RM-RS subgroups based on the x Cell algorithm. E Correlation heatmap of RM-RS and endothelial cell marker gene expression. F The expression of CD34 and CXCL12 in different risk subgroups. G Multiple immunofluorescence analysis (MIF) of different risk subgroups. The staining of these genes was quantified by corrected total cell fluorescence (CTCF). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001