Fig. 4

The Molecular Function and Mechanism of RM-RM in BLCA. A Gene set enrichment analysis (GSEA) of drug resistance and metabolism-related score (RM-RS) and BLCA occurrence, metastasis and progression signaling pathways. p < 0.05 B Heatmap of differentially expressed genes (DEGs) by comparing the expression between the high and low RM-RS groups. p < 0.05 and |FC|> 2. Blue represents the low-risk subgroup and red represents the high-risk subgroup. C Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of these DEGs. D Single-sample gene set enrichment analysis (ssGSEA) of metabolic pathway gene sets in the TCGA BLCA database. Heatmap of Metabolic pathway score of TCGA BLCA patients. E The violin plot shows the difference analysis of the metabolic scores of the high- and low-risk subgroups. F Metabolism-related gene sets enriched in the high- and low-risk subgroups (p < 0.05)